Carbohydrate-dependent interaction between AMY1A/AMY2B copy number variation and APOA5 rs651821 associated with hypertriglyceridemia in Korean middle-aged adults.

BMC Nutr · 2026 · PMC13360801 · PMID 42152161

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a marginal trendno p-value reported

Results In the fully adjusted model, the independent association of AMY1A / AMY2B duplication with hypertriglyceridemia was attenuated to a marginal trend, whereas APOA5 rs651821 C-carrier showed a significant independent association (OR = 2.00; 95% CI: 1.39–2.88).

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nominally significantno p-value reported

The three-way interaction was nominally significant but did not remain significant after FDR correction.

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