Malignancy as a Predictor and Potential Modifier of Laboratory Biomarker Prognostic Value in Acute Pulmonary Embolism.

Diagnostics (Basel) · 2026 · PMC13361538 · PMID 42449911

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hedged sentences

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

borderline significantp = 0.051so close (0.05 < p ≤ 0.1)

Patients with malignancy had higher CRP levels, D-dimer, and TLC, as well as lower lymphocyte count, Hb, hematocrit, and CrCl (CrCl borderline significant, p = 0.051).

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did not reach statistical significanceno p-value reported

Although elevated odds ratios were also observed across CRP and D-dimer quartiles in malignant patients, these associations did not reach statistical significance when compared with Q1 ( Figure 1 ). 3.4.

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highly significantno p-value reported

Glucose shows the opposite pattern: in non-malignant patients, quartile-based increases in glucose produce only a modest, non-significant rise in risk, whereas in the oncological cohort, risk rises sharply and becomes highly significant only in the highest quartile (Q4 vs.

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