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Evaluation of Intravenous Lipid Emulsion as an Adjunctive Antidote in Experimental Fentanyl Toxicity: Comparison with Naloxone in a Rat Model.

Int J Mol Sci · 2026 · PMC13361572 · PMID 42450250

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While all treatments reduced fentanyl-induced effects toward control values at 15 min, naloxone did not reach statistical significance, whereas ILE and the combination demonstrated clearly significant effects.

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