Incorporation of Organosilicon Motifs in Natural and Synthetic Small Molecules for Anticancer Therapeutics: Current Perspectives and Future Opportunities in Drug Design.

Molecules · 2026 · PMC13362805 · PMID 42451712

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a clear trendno p-value reported

In vitro antiproliferative assays across multiple cancer cell lines, including HCT-116 and HT-29 (colorectal) and SK-OV-3 (ovarian), revealed a clear trend of diminished potency following silylation.

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