A Heat-Inactivated Two-Strain <i>Lacticaseibacillus paracasei</i> Fermented Milk as a Postbiotic for Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial.

reported that although constipation severity scores and bowel movement frequency improved from baseline after Lactobacillus casei Shirota intervention, the differences compared with placebo did not reach statistical significance [ 22 ].

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