Deep Proteomic Analysis With Machine Learning Identifies Aqueous Humor Biomarkers of ADAMTSL4-associated Congenital Ectopia Lentis.

Invest Ophthalmol Vis Sci · 2026 · PMC13367205 · PMID 42423409

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant

SDC4 was excluded from the technical confirmation because its target peptides failed quality-control assessment due to low signal intensity and insufficient specificity, and ADAMTS3 did not reach statistical significance in iPRM quantification ( P > 0.05).

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