Statistical power for the nominally significant MR estimates was calculated using the mRnd online calculator ( https://shiny.cnsgenomics.com/mRnd/ ), incorporating the sample size of the outcome GWAS, the proportion of variance in the exposure explained by the IVs (R2), and the observed odds ratio, with a Type-I error rate (α) set at 0.05 [ 33 ].
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Causal effects of oral microbiome traits on female reproductive diseases: a two-sample Mendelian randomization study.
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