IL-1β-mediated interaction between Müller cells and microglia through CXCL1/5-CXCR2 aggravates visual dysfunction in experimental glaucoma.

However, in the peripheral region, although a trend toward increased surviving RGCs was observed following anti-CXCL1 treatment, this improvement did not reach statistical significance compared to the IgG2A-injected control group.

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In contrast, in IL-1β-injected retinas, no significant differences were observed in the mRNA expression levels of CXCL2, CXCL6, CXCL7, CXCL9, CXCL10, CXCL11, CXCL14, and CXCL16, although CXCL9 and CXCL10 showed an increasing trend at G4d (Fig.

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