Two Decades of Light-Chain Amyloidosis: Real-World Trends in Diagnosis, Treatment, and Survival.

J Hematol · 2026 · PMC13375427 · PMID 42490803

Europe PMC DOI

hedged sentences

0.0490

closest p · 1.0× alpha

0.1130

boldest claim

The sentences

borderline significantP = 0.049actually significant

One-year mortality showed a borderline significant reduction (OR = 0.75; 95% CI, 0.57–1.00; P = 0.049), while 10-year mortality was markedly improved (OR = 0.67; 95% CI, 0.53–0.86; P = 0.002).

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showed a trendP = 0.113not close (p > 0.1)

Kaplan–Meier analysis showed a trend toward improved survival (HR = 0.89; log-rank P = 0.113) ( Fig. 3a ).

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