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Rare Variants in Purinergic P2X Receptor Genes <i>(P2RX4, P2RX5, P2RX7)</i> in Individuals With Autism Spectrum Disorder: An Exploratory Study.

Hum Mutat · 2026 · PMC13379949 · PMID 42471841

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Although the primary ABC‐Core outcome did not reach statistical significance, the 10 mg/kg arm demonstrated meaningful clinical benefit on the CGI‐I scale, with favorable responses particularly in younger children and those with less severe baseline symptoms.

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