Barely Significant
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Genetically Proxied Biological Aging and Risk of Hypertrophic Scar/Keloid-Coded Phenotypes: An Exploratory Two-Sample Mendelian Randomization Study.

Clin Cosmet Investig Dermatol · 2026 · PMC13380249 · PMID 42472084

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nominally significantno p-value reported
19 , 27 Multivariable Mendelian Randomization Analysis For exposures with nominally significant associations in both primary and replication analyses, we conducted MVMR analyses to test whether the observed effect was mediated by major fibrogenic factors, including MMP2, MMP9, TIMP1, TIMP2, TGFB1, TGFBR1, TGFBR2, SMAD2, SMAD3, and CTGF.

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