Bone anabolic effects of tibial loading in combination with dual sclerostin and Dkk1 antibodies in aged mice.

JBMR Plus · 2026 · PMC13384640 · PMID 42519820

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0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < .0001actually significant

Two-factor ANOVA indicated that antibody treatment had a strong and highly significant effect on Ec.MS/BS, Ec.MAR, and Ec.BFR/BS (“Rx” main effect, p < .0001; Figure 3D ).

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near-significantno p-value reported

Loading (main effect) also had a significant or near-significant inhibitory effect on Sost and Dkk1 expression, respectively ( Figure 1F and G ).

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