Del immune V and microbiome restructuring in colorectal cancer surgery: a randomized double blind placebo controlled trial.

Intra-group analysis demonstrated highly significant reductions in CRP from baseline to Week 8 (Del-Immune V: p < 0.001; Control: p = 0.001).

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At the taxon level, the nominally significant decreases in Tissierellia -associated genera (Peptostreptococcus , Parvimonas, Peptoniphilaceae ) and in the Fusobacterium nucleatum group are consistent with the observed decline in CRC- and inflammation-associated taxa in the Del-Immune V arm, as captured by both the guild analysis and the CRC dysbiosis index.

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