Barely Significant
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Global Burden of Cardiovascular Diseases in Young Adults Aged 20-24 Years, from 1990-2021: An Analysis of the Global Burden of Disease Study 2021.

CJC Open · 2026 · PMC13386730 · PMID 42483021

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a significant trendno p-value reported
4 Studies have reported 2 a significant trend in DALYs caused by high systolic blood pressure in young people aged 20-24 years.

also in 9,775 other papers

an increasing trendno p-value reported
Over the past 30 years, the stroke burden declined significantly in all of the regions, except for the ASIR in North Africa and the Middle East, which showed an increasing trend ( Supplemental Table S4 ).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.