Prenatal and neonatal housing conditions affect anxiety-like behavior in adulthood in rats and interact with brain-derived neurotrophic factor (BDNF) Val66Met to alter expression of BDNF and stress markers in the ventral hippocampus.

Front Mol Neurosci · 2026 · PMC13388326 · PMID 42488725

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0.0520

closest p · 1.0× alpha

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boldest claim

The sentences

a strong trendp = 0.052so close (0.05 < p ≤ 0.1)

Analysis of time spent in the outer zone ( Supplementary Table 4 ) predictably showed the opposite trends with males spending more time in the outer zone than females [ F (1,109) = 18.11, p < 0.001, η p 2 = 0.142] and a strong trend for HE rats to spend more time in the outer zone than LE rats [ F (1,109) = 3.87, p = 0.052, η p 2 = 0.034].

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