1 Adding HFH outcomes (number of HFHs and time to first HFH) provided additional discrimination between patients, resulting in more wins with digitoxin at these levels and nominally significant win ratios.
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The sentences
1 The trial met its primary objective, demonstrating superiority of digitoxin over placebo for time to first heart failure hospitalization (HFH) or all-cause death (whichever occurred first), with a favorable trend in all-cause mortality. 1 To further support the robustness of these findings and capture treatment benefit across outcomes ordered by clinical relevance, we report results from win ratio analyses.