Distinguishing central precocious puberty from nonprogressive breast development: adiposity and DXA body composition.

J Endocr Soc · 2026 · PMC13392474 · PMID 42495577

Europe PMC DOI

hedged sentences

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

did not reach statistical significanceP = .081so close (0.05 < p ≤ 0.1)

Excess weight (overweight/obesity) was more common in girls with nonprogressive premature breast development than in those with central precocious/early puberty (58.1% vs 37.7%), although this difference did not reach statistical significance ( P = .081).

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a nonsignificant trendno p-value reported

Among normal-weight girls, those with CPP/EP had higher body weight ( P = .03) and greater ΔH–TH SDS ( P = .009) than their peers with npPBD, as well as more advanced bone age ( P = .02) and higher IGF-1 SDS ( P = .001); they also showed a nonsignificant trend toward a larger uterine anteroposterior diameter.

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