Potential Survival Benefit of Neoadjuvant Docetaxel, Cisplatin and 5-Fluorouracil Therapy in Patients With Esophageal Squamous Cell Carcinoma With Multiple Lymph Node Metastases: A Single-Institute Propensity Score Analysis.

Ann Gastroenterol Surg · 2026 · PMC13394455 · PMID 42495658

Europe PMC DOI

hedged sentence

0.0390

closest p · 0.8× alpha

0.0390

boldest claim

The sentences

nominally significantp = 0.039actually significant

Subgroup analysis showed that patients with cN2‐3 had a significant survival benefit with NAC‐DCF (HR 0.51; 95% CI, 0.34–0.76) in the IPW analysis, whereas no clear association was observed in those with cN0–1 (HR 0.93; 95% CI, 0.62–1.34), with a nominally significant interaction by clinical N stage ( p = 0.039).

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