Barely Significant
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KRAS G12C inhibitors in KRAS<sup>G12C</sup>-mutated solid tumors: an immunologically informed systematic review and reconstructed individual patient data meta-analysis.

Front Immunol · 2026 · PMC13396023 · PMID 42500683

Europe PMCDOI
1
hedged sentence
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

of marginal significanceP = 0.054so close (0.05 < p ≤ 0.1)
In the ≥50% subgroup, the PFS improvement was of marginal significance and did not reach the statistical threshold (HR = 0.68, 95% CI: 0.47-1.01; P = 0.054).

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