Efficacy and Safety Profile of a Rituximab, Methotrexate, and Thiotepa-Based Regimen in Newly Diagnosed Primary CNS Lymphoma.

Int J Cancer · 2026 · PMC13397143 · PMID 41999193

Europe PMC DOI

hedged sentence

0.0690

closest p · 1.4× alpha

0.0690

boldest claim

The sentences

did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

The proportion of patients with multifocal lesions was also higher in the R‐MT group than in the R‐M ± A group; although this difference did not reach statistical significance ( p = 0.069), when considered alongside the above baseline features, it suggests an overall higher prognostic risk profile in the R‐MT cohort.

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