Barely Significant
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The melanocytic transcriptomic state is independently associated with poor overall survival in patients with metastatic melanoma.

Sci Adv · 2026 · PMC13398476 · PMID 42497279

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showed a trendno p-value reported
ICI treatment was significantly associated with improved MSS in “melanocytic-low” patients and showed a trend toward benefit in the melanocytic-high group ( Fig. 5B ).

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