A predictive corticospinal model for pain perception.

Cell Rep Med · 2026 · PMC13400141 · PMID 42309066

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0630

boldest claim

The sentences

highly significantp < 0.001actually significant

Critically, the interaction was highly significant ( β = 0.29, Z = 4.07, p < 0.001, 95% CI = 0.15–0.44), indicating that the slope linking CsPIP output to subjective intensity differed across conditions.

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failed to reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)

Notably, the traditional NPS failed to reach statistical significance in capturing this effect ( r = 0.34, p = 0.063), highlighting a stronger predictive performance by CsPIP.

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