Serum adropin as a potential renoprotective factor in diabetic kidney disease: evidence from a Chinese elderly cohort and an experimental mouse model.

When adropin was categorized into quartiles (Q1 ≤ 3.94 ng/mL; 3.94 < Q2 ≤ 5.20; 5.20 < Q3 ≤ 6.55; Q4 > 6.55), participants in the highest quartile (Q4) had significantly lower odds of DKD than those in Q1 across all models, and a significant trend was observed with increasing adropin levels (P for trend < 0.01) ( Table 2 ; Supplementary Figure 1A ).

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