Clinical and PET/CT metabolic imaging characteristics across the evolving spectrum of visceral leishmaniasis and associated hemophagocytic lymphohistiocytosis.

Front Immunol · 2026 · PMC13402202 · PMID 42516382

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a clear trendno p-value reported

Despite the absence of a clear trend, the Grey Zone patient exhibited a markedly elevated IL-6 level (221.30 pg/mL), comparable to the highest value in the VL-HLH group (167.40 pg/mL), and also showed the highest splenic SUVmax (9.85), suggesting an inflammatory and metabolic phenotype more closely aligned with the VL-HLH group.

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