Peripheral T-Cell Receptor β Repertoire Dynamics Correlate with Response to Anti-PD-L1 Therapy in Non-Small Cell Lung Cancer.

Cancers (Basel) · 2026 · PMC13406223 · PMID 42512307

Europe PMC DOI

hedged sentences

0.0849

closest p · 1.7× alpha

0.0849

boldest claim

The sentences

a trend toward significancep = 0.0849so close (0.05 < p ≤ 0.1)

Histological type showed a trend toward significance, with squamous histology associated with a higher hazard than adenocarcinoma (HR = 2.58, 95% CI: 0.92–8.33; p = 0.0849).

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nominally significantno p-value reported

In this context, although several TRBV genes exhibited nominally significant differences between patient subgroups, only a restricted number remained significant after the Benjamini–Hochberg correction for multiple testing.

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