Prolonged Ischemia Induces Cellular Stress, Stimulates Extracellular Matrix Remodeling and Compromises the Viability of Human Cancellous Bone Grafts.

The expression of CXCL8 showed a strong trend towards upregulation, and the expression of JUN and DUSP1 was significantly upregulated after 60 and 90 min when compared to the early time points phb and 30 min ( Figure 4 a,b).

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