Prognostic Role of TERT Mutations in Chondrosarcoma: Associations with Dedifferentiation, Survival, and IDH/TERT Co-Mutations.

Cancers (Basel) · 2026 · PMC13406695 · PMID 42512337

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hedged sentences

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

a strong trendp = 0.077so close (0.05 < p ≤ 0.1)

In contrast, TP53 mutations demonstrated a strong trend toward increased recurrence risk (OR = 7.0, 95% CI 1.16–135.12; p = 0.077), although this did not reach statistical significance ( Figure 4 B).

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a possible trendno p-value reported

This suggests a possible trend toward greater recurrence among TERT -mutated tumors, but the small number of TERT -positive cases limits statistical interpretation ( Figure A3 ). 3.4.

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