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Liposomal bupivacaine versus ropivacaine for surgical site infiltration in lumbar fusion: a prospective randomized controlled trial.

Ann Med · 2026 · PMC13410536 · PMID 42504098

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Interestingly, while the overall pain trajectory differed between groups, pairwise comparisons at individual time points did not reach statistical significance, suggesting that conventional time-point analyses might underestimate treatment effects in postoperative pain studies.

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