Rab GTPases drive ligand-independent NOTCH1 activation via altered endocytic trafficking in chronic lymphocytic leukemia.

Hemasphere · 2026 · PMC13410950 · PMID 42524323

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did not reach statistical significanceno p-value reported

CLL cells displayed significantly higher levels of Rab5 and Rab11 compared to HD B cells and a modest increase of Rab7 levels that did not reach statistical significance (Figure S13 ).

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