Joint Association of Functional Impairment and Depression with Advanced Cardiovascular-Kidney-Metabolic Syndrome: A Cross-Sectional and Cohort Study Using Two Large Datasets.

In the NHANES sample ( Figure 2 ), only hypertension demonstrated a nominally significant interaction with the joint association of IADL impairment and depression ( p = 0.03); however, this was not replicated in the CHARLS cohort ( Figure 3 ).

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