Genotype-based severity scoring system in Wolfram Syndrome: correlation with onset of cardinal symptoms and <i>WFS1</i> gene variant types.

Front Genet · 2026 · PMC13412279 · PMID 42524523

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a clear trendno p-value reported

Diabetes mellitus followed a clear trend with earlier ages of onset correlating to higher severity scores, the only exception being severity score 3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Genotype-based severity scoring system in Wolfram Syndrome: correlation with onset of cardinal symptoms and &lt;i&gt;WFS1&lt;/i&gt; gene variant types.

The sentences

Genotype-based severity scoring system in Wolfram Syndrome: correlation with onset of cardinal symptoms and <i>WFS1</i> gene variant types.