Efficacy and safety of recombinant human bone morphogenetic protein-2 biomaterials in promoting bone regeneration: A systematic review and meta-analysis.

Stomatognathic defects (Figure 6a) showed a positive trend after pooling, but it did not reach statistical significance (random-effects RR = 1.06, 95% CI 0.96-1.18; I 2 = 38.3%; prediction interval 0.93-1.21).

also in 11,005 other papers

Using autologous bone as the reference, network meta-analysis (Figure 9) showed that the overall bone regeneration success rate of rhBMP-2 (OR = 1.53, 95% CI 0.54-4.33) and other bone substitute materials (OR = 1.42, 95% CI 0.39-5.21) was not statistically significantly higher than that of autologous bone, but both showed a clear trend of superiority.

also in 19,460 other papers