Causal Effects of Circulating Inflammatory Proteins on Postmenopausal Atrophic Vaginitis in European Populations: A Mendelian Randomization Study with Transcriptomic Validation.

To prioritize findings with the greatest evidence of robustness, proteins were considered candidate causal factors if they met two simultaneous criteria: (1) a nominally significant IVW p-value (p < 0.05), and (2) directional consistency of effect estimates across all four MR methods.

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