Sex-aware causal inference assessment of the immune system in complex neurodegenerative diseases.

We then applied sensitivity analyses for nominally significant results ( P -value < 0.05), namely: heterogeneity test (Cochran’s Q), horizontal pleiotropy (MR Egger intercept), detection of outliers with MR Pleiotropy Residual Sum and Outlier test (MR-PRESSO v1.0) 46 and directionality validation.

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