Locus coeruleus TDP-43 pathology in a community-based cohort: Clinical and pathological correlates.

J Neuropathol Exp Neurol · 2026 · PMC13440673 · PMID 42008717

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nominally significantno p-value reported

Increasing quantitative LC pTDP-43 burden demonstrated a nominally significant positive association with caregiver rated symptoms of depression, based on lesion counts rather than the binary presence or absence of LC pTDP-43 pathology.

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