Barely Significant
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Severity-stratified vasopressor-escalation strategies in septic shock: a cross-fitted doubly robust analysis with external replication.

Front Pharmacol · 2026 · PMC13446109 · PMID 42565049

Europe PMCDOI
1
hedged sentence
0.0110
closest p · 0.2× alpha
0.0110
boldest claim

The sentences

nominally significantp = 0.011actually significant
Among the secondary strata, only the absence of chronic liver disease ( p = 0.001) survived a conservative Bonferroni threshold of 0.006 for the family of secondary tests; the age ≥65 contrast, though nominally significant ( p = 0.011), did not.

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