highly significantP < 2.2e−16
A comparison of activation strength in both assays revealed an intermediate (Pearson's correlation coefficient of 0.58) but highly significant correlation ( P < 2.2e−16) of activation values ( Figure 1B ).
A comparison of activation strength in both assays revealed an intermediate (Pearson's correlation coefficient of 0.58) but highly significant correlation ( P < 2.2e−16) of activation values ( Figure 1B ).
With an average copy number of ∼4000 proteins per cell the Y2H activators confirmed this finding and even showed a trend towards lower abundance the stronger the activation was ( Figure 2C ).