approached significancep < 0.07
The day: night differences in the area density (μm 2 /μm 2 ) of the Bu-1 + microglia/macrophages within pineal tissue approached significance as analyzed by a two-tailed Student's t -test (p < 0.07, n = 10 for each time point) with a 43% decline at the light: dark interphase (0.020 ± SEM 0.003) compared to the dark: light interphase (0.035 ± SEM 0.007).