Evidence-based prescribing of statins: a developing world perspective.

And although the reduction in primary end point in the A to Z Trial [ 14 ] (which compared immediate versus delayed treatment with a statin after an acute coronary syndrome) did not reach statistical significance, the number needed to treat to prevent one primary end point (NNT), was 43.

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This was similar to the NNT of 45 in the Treating to New Targets Trial (17), which produced a highly significant reduction in primary end point ( Table 3 ).

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