At present, we have level IB evidence that CVVH at 35 ml/kg/hour is beneficial in patients with ARF, and a suggestion that CVVH >45 ml/kg/hour might be particularly helpful if sepsis is also present (although this effect did not reach statistical significance) [ 8 ].
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Pro/con clinical debate: is high-volume hemofiltration beneficial in the treatment of septic shock?
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