Assessing the accuracy of ancestral protein reconstruction methods.

PLoS Comput Biol · 2006 · PMC1480538 · PMID 16789817

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near-significantp = 0.06so close (0.05 < p ≤ 0.1)

ML shows a statistically significant (correlation coefficient −0.61, p = 0.02) increase in reconstruction bias with the depth of the node (measured as the shortest distance to an existent sequence); MP shows a near-significant increase (correlation coefficient −0.49, p = 0.06), while BI is not significantly statistically correlated with node depth ( p = 0.49).

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