Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B.

Arthritis Res Ther · 2006 · PMC1526569 · PMID 16356189

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0.0001

closest p · 0.0× alpha

0.0001

boldest claim

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highly significantP = 0.0001actually significant

Highly significant linkage disequilibrium was seen between FCGR3B and FCGR2B in both populations (UK Caucasian: D' = -0.68, P = 0.0001; North Indian/Pakistani: D' = -0.52, P = 0.0001).

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failed to reach statistical significanceno p-value reported

In the North Indian/Pakistani population there was a 6% increase in the FCGR3A – FCGR3B 158V-NA2 haplotype, but this failed to reach statistical significance.

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