Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure.

Arthritis Res Ther · 2006 · PMC1526609 · PMID 16507172

Europe PMC DOI

hedged sentence

0.4200

closest p · 8.4× alpha

0.4200

boldest claim

The sentences

did not reach statistical significanceP = 0.42not close (p > 0.1)

Baseline acute phase reactants were higher for original methotrexate courses than for re-employed courses of methotrexate, but this difference did not reach statistical significance (CRP, P = 0.42; ESR, P = 0.07).

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