Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus.

Arthritis Res Ther · 2006 · PMC1526610 · PMID 16507174

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did not reach statistical significanceno p-value reported

Although the increase in CD40 expression that we found in pDCs, after the onset of lupus, did not reach statistical significance with non-parametric tests, we cannot exclude CD40-CD40L interactions as a mechanism by which pDCs are induced to overproduce type I IFN and sustain autoimmunity.

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