Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro.

Although the synapses appear to be weak, in numbers they account for two thirds of the GABAergic inputs to a given MSN neuron [ 9 , 16 ], so on a network level their function is likely to be quite significant [ 11 , 16 ].

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