Barely Significant
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Can clinical trials requiring frequent participant contact be conducted over the Internet? Results from an online randomized controlled trial evaluating a topical ointment for herpes labialis.

J Med Internet Res · 2004 · PMC1550589 · PMID 15111272

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Although the DSS treatment group had a shorter mean outbreak duration (6.6 vs 7.7 days, P = .2) and fewer mean days to crust formation (3.5 vs 4.9, P = .1), these differences did not reach statistical significance.

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