Barely Significant
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Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis.

Crit Care · 2006 · PMC1550818 · PMID 16420659

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a significant trendno p-value reported
Namely, there was no indication that PC deficiency would associate with MOF after its diagnosis and, further, there was a significant trend for improvement of PC homeostasis during the course of MOF.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.