Barely Significant
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Frequency of adverse events after vaccination with different vaccinia strains.

PLoS Med · 2006 · PMC1551910 · PMID 16933957

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a clear trendno p-value reported
Results Relationship between Study Period and the Reported Incidence of PVE after Primary Vaccination The estimated incidences of PVE after primary vaccination in studies conducted in different periods showed a clear trend toward lower incidences in more-recent periods ( Figure 1 A).

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