Multiple-site carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice.

C-cell adenomas or carcinomas (com- bined) in male rats occurred with a negative trend (p = 0.039) and the incidences in the dosed groups were not significantly different from that in the vehicle control group (vehicle control, 9/49, 18%; low dose, 5/47, 11%; mid dose, 4/46, 9%; high dose, 2/47, 4%).

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