this trend was also observed for mmp-9, but did not reach statistical significance, probably due to the very wide standard deviation (4.0 ± 1.3 versus 28.6 ± 71.2 ng/mg in normal individuals and in the patients, respectively; > P = 0.07).
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Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
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